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A cascade involving edema, an inflammatory response, ROS/reactive nitrogen species (RNS) production, glutamate-mediated toxic effects, neuronal apoptosis, ferroptosis, and glial scarring occurs after SCI [31,32,33]

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Nevertheless, understanding the long-term implications for muscle preservation and functional outcomes remains important, particularly in older adults, patients with chronic kidney disease, and populations at risk of sarcopenic obesity [9]

Recent developments in glioblastoma therapy: oncolytic viruses and emerging future strategies